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6. Comparison with Avid/Vista



Comparison between phyloMOD.pl and avid/Vista.

As you can notice peaks in Vista are identified by module/hits in phyloMOD.pl.
In phyloMOD.pl output you can see both species coordinates while in Vista visualizations you have just one axis with coordinates for a
single reference sequence (in this case mouse).

In the next picture you can see that modules can cross each other since DNA bendability allows such a solution.
You can even notice that a potential regulatory region in the upstream region of mouse moved downstream in chicken.


Hence single hits are determined by local alignment through bl2seq (blast two sequences) ans with subsequente computation modules (or highly conserved regions) are detected.


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